Cervical non-invasive vagus nerve stimulation (nVNS) for preventive and acute treatment of episodic and chronic migraine and migraine-associated sleep disturbance: preliminary findings from a prospective observational cohort study

Table 2 Demographic and baseline characteristics

Patient No.	Sex	Age, years	Migraine Type	Number of Attacks per Month	Pain Intensity (VAS) Score	Number of Headache Days per Month	MIDAS Grade (score)	BDI Score	Prophylactic Medications	Acute Medications + Time to Achieve Pain Relief	BMI, kg/m²	Global PSQI Score
1	f	36	EM+	6	6	10	III (18)	18	4 Classes + Mg + Botox®	Triptan + 60 min	24	5
2	f	66	CM-	6	8	20	IV (45)	19	4 Classes + Botox	NSAID + 90 min	23	12
3	f	41	CM-	7	8	20	IV (39)	34	4 Classes	Triptan + 60 min	31	12
4	m	70	CM-	7	7	15	IV (39)	15	Calcium channel blocker	NSAID + 45 min	25	2
5	f	56	CM+	17	8	18	IV (51)	17	N/A	Triptan + 60 min	25	17
6	f	60	CM-	8	8	22	IV (44)	16	4 Classes + Botox	Triptan + 60 min	24	7
7	f	35	EM-	4	8	9	III (19)	8	4 Classes + Botox	Triptan + 60 min	17	8
8	m	50	EM-	5	7	9	IV (37)	23	4 Classes + Botox	NSAID + 160 min	40	6
9	f	50	EM-	3	9	9	IV (45)	5	4 Classes + Botox	Triptan + 30 min	22	7
10	f	35	CM-	12	8	15	IV (36)	11	4 Classes + Botox	Triptan + 60 min	22	12
11	m	39	EM-	4	8	12	III (19)	21	Calcium channel blocker + Mg + Ca⁺⁺	NSAID + 150 min	29	7
12	f	52	EM-	4	8	12	III (19)	21	4 Classes + Mg	Triptan + 150 min	23	3
13	f	45	CM-	15	8	18	IV (33)	25	4 Classes + Botox	NSAID + 45 min	23	17
14	f	54	EM-	4	8	12	III (18)	17	4 Classes + Mg	Triptan + 120 min	25	4
15	f	60	EM-	10	8	14	III (19)	18	4 Classes + Mg	Triptan + 60 min	18	5
16	f	60	EM-	5	7	14	III (16)	16	4 Classes + Botox	Triptan + 120 min	20	11
17	f	59	CM+	10	8	15	III (18)	16	4 Classes + Botox	Triptan + 90 min	22	6
18	m	72	CM-	9	8	18	III (17)	15	4 Classes	NSAID + 90 min	22	8
19	f	60	CM-	6	8	20	IV (44)	16	4 Classes + Botox	Triptan + 60 min	24	6
20	f	62	EM-	4	7	12	III (16)	15	4 Classes + Botox	Triptan + 120 min	20	10

Abbreviations: BDI Beck Depression Inventory, BMI body mass index, Ca ⁺⁺ calcium, CM chronic migraine, EM episodic migraine, f/m female/male, Mg magnesium, MIDAS Migraine Disability Assessment, NSAID nonsteroidal anti-inflammatory drug, PSQI Pittsburgh Sleep Quality Index, VAS visual analogue scale, 4 Classes β-blocker, anticonvulsant, tricyclic antidepressant, calcium channel blocker, −/+ without aura/with aura

ISSN: 1129-2377