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Table 3 ROC analyses of the PHQ-9 and PHQ-2 for the diagnosis of current MDD as determined by the MINI-Plus 5.0.0

From: Validation of the Patient Health Questionnaire-9 (PHQ-9) and PHQ-2 in patients with migraine

Cut off score Sensitivity Specificity PPV NPV AUC SE 95 % CI p value
PHQ-9         
>5 87.2 67.3 53.1 92.6 0.775 0.043 0.690–0.859 <0.001
>6 82.1 75.3 58.2 90.9 0.787 0.044 0.700–0.873 <0.001
>7 79.5 81.7 64.6 90.5 0.806 0.044 0.720–0.892 <0.001
>8 71.8 87.1 70.0 88.0 0.794 0.047 0.702–0.887 <0.001
>9 64.1 90.3 73.5 85.7 0.772 0.050 0.674–0.870 <0.001
PHQ-2         
>1 89.7 63.4 50.7 93.7 0.766 0.043 0.682–0.850 <0.001
>2 66.7 90.3 74.3 86.6 0.785 0.049 0.689–0.881 <0.001
>3 48.7 97.8 90.5 82.0 0.733 0.054 0.626–0.839 <0.001
  1. ROC Receiver operating characteristic, PHQ-9 Patient Health Questionnaire-9, PHQ-2 Patient Health Questionnaire-2, MDD Major Depressive Disorder, MINI-Plus 5.0.0 Mini International Neuropsychiatric Interview-Plus Version 5.0.0, PPV positive predictive value, NPV negative predictive value, AUC area under the curve