ICHD-2 | p value | ICHD-3 beta | p value | |||
---|---|---|---|---|---|---|
Sleep apnoea headache (n = 29) | No sleep apnoea headache (n = 206) | Sleep apnoea headache (n = 39) | No sleep apnoea headache (n = 196) | |||
Age (years) | 50.4 ± 10.6 | 55.4 ± 11.6 | 0.028 | 49.3 ± 10.1 | 55.9 ± 11.6 | 0.0012 |
BMI (kg/m2) | 31.7 ± 10.0 | 28.2 ± 7.3 | 0.084 | 31.5 ± 9.0 | 28.1 ± 7.4 | 0.011 |
Sex (M/F) | 21/8 | 169/37 | 0.22 | 30/9 | 160/36 | 0.50 |
Education (years) | 14.6 ± 2.9 | 13.3 ± 2.7 | 0.028 | 14.8 ± 3.4 | 13.2 ± 2.6 | 0.0073 |
Caffeine (cup/day) | 2.6 ± 1.9 | 2.9 ± 2.6 | 0.54 | 2.7 ± 1.8 | 2.9 ± 2.6 | 0.73 |
Smoking, n (%) | 0.28 | 0.17 | ||||
Never | 9 (31.0) | 87 (42.2) | 13 (33.3) | 83 (42.3) | ||
Past | 12 (41.4) | 85 (41.3) | 15 (38.5) | 82 (41.8) | ||
Current | 8 (27.6) | 34 (16.5) | 11 (28.2) | 31 (15.8) | ||
Alcohol, n (%) | 0.040 | 0.0057 | ||||
Never | 8 (27.6) | 70 (34.0) | 11 (28.2) | 67 (34.2) | ||
< 1 day/week | 14 (48.3) | 50 (24.3) | 19 (48.7) | 45 (23.0) | ||
1-2 days/week | 4 (13.8) | 22 (10.7) | 5 (12.8) | 21 (10.7) | ||
3-5 days/week | 2 (6.9) | 27 (13.1) | 3 (7.7) | 26 (13.3) | ||
6-7 days/week | 1 (3.4) | 37 (18.0) | 1 (2.6) | 37 (18.9) | ||
AHI (/h) (before CPAP treatment) | 51.6 ± 22.6 | 55.3 ± 25.2 | 0.46 | 56.6 ± 24.9 | 54.5 ± 24.9 | 0.63 |
3 % ODI (/h) | 41.5 ± 23.7 | 45.4 ± 26.6 | 0.47 | 46.9 ± 26.7 | 44.5 ± 26.2 | 0.61 |
Arousal index (/h) | 47.0 ± 17.5 | 56.1 ± 48.1 | 0.41 | 51.3 ± 20.6 | 55.7 ± 48.9 | 0.66 |
Morning headache | 29 (100) | 19 (9.2) | <0.001 | 39 (100) | 9 (4.6) | <0.001 |
ESS (before CPAP treatment) | 8.7 ± 4.7 | 8.5 ± 5.2 | 0.88 | 8.6 ± 4.6 | 8.5 ± 5.3 | 0.90 |
PSQI global score | 5.8 ± 2.6 | 5.1 ± 3.1 | 0.23 | 5.9 ± 2.9 | 5.0 ± 3.0 | 0.085 |
PSQI component score | ||||||
C1, Sleep quality | 1.4 ± 0.6 | 1.1 ± 0.7 | 0.052 | 1.3 ± 0.7 | 1.1 ± 0.7 | 0.064 |
C2, Sleep latency | 0.8 ± 1.0 | 0.6 ± 0.9 | 0.52 | 0.8 ± 1.0 | 0.6 ± 0.9 | 0.28 |
C3, Sleep duration | 1.4 ± 0.9 | 1.1 ± 0.9 | 0.055 | 1.4 ± 0.9 | 1.1 ± 0.9 | 0.062 |
C4, Habitual sleep efficiency | 0.3 ± 0.7 | 0.2 ± 0.7 | 0.48 | 0.3 ± 0.6 | 0.2 ± 0.7 | 0.80 |
C5, Sleep disturbances | 1.0 ± 0.6 | 0.9 ± 0.5 | 0.20 | 0.9 ± 0.6 | 0.9 ± 0.5 | 0.39 |
C6, Use of sleeping medication | 0.3 ± 0.8 | 0.4 ± 1.0 | 0.54 | 0.5 ± 1.0 | 0.4 ± 1.0 | 0.51 |
C7, Daytime dysfunction | 0.7 ± 0.8 | 0.7 ± 0.9 | 0.62 | 0.7 ± 0.8 | 0.7 ± 0.9 | 0.93 |
BDI-II | 11.4 ± 6.9 | 9.1 ± 7.3 | 0.10 | 11.5 ± 7.1 | 8.9 ± 7.3 | 0.042 |
Residual AHI after CPAP treatment (/h)a | 3.5 ± 2.3 | 3.7 ± 2.5 | 0.67 | 3.6 ± 2.5 | 3.7 ± 2.4 | 0.88 |
CPAP responders (residual AHI < 10), n (%) | 29 (100) | 202 (98.1) | 1.0 | 38 (97.4) | 193 (98.5) | 0.65 |
CPAP treatment period (/m) | 29.0 ± 29.4 | 36.4 ± 29.0 | 0.20 | 29.2 ± 28 | 36.8 ± 29.2 | 0.14 |
Daily CPAP use (h) | 5:03 ± 1:24 | 5:04 ± 1:38 | 0.98 | 4:45 ± 1:33 | 5:07 ± 1:36 | 0.19 |
CPAP usage > 4 h/d, n (%) | 16 (55.2) | 106 (51.5) | 0.71 | 19 (48.7) | 103 (52.6) | 0.66 |