Table 3 Differences of genotypes distributions between Migraine groups and multiple inheritance models using the WEB Tool SNPStats ( http://bioinfo.iconcologia.net/snpstats/start.htm )

Codominant

G/G

1.00

0.65

G/G

1.00

0.44

G/G

1.00

0.87

A/G

1.02 (0.51-2.01)

A/G

1.25 (0.75-2.08)

A/G

1.16 (0.67-2.01)

A/A

1.43 (0.62-3.32)

A/A

1.51 (0.79-2.89)

A/A

1.11 (0.53-2.29)

Dominant

G/G

1.00

0.72

G/G

1.00

0.26

G/G

1.00

0.61

A/G-A/A

1.12 (0.59-2.13)

A/G-A/A

1.32 (0.81-2.13)

A/G-A/A

1.14 (0.68-1.94)

Recessive

G/G-A/G

1.00

0.35

G/G-A/G

1.00

0.34

G/G-A/G

1.00

0.97

A/A

1.42 (0.68-2.95)

A/A

1.31 (0.74-2.32)

A/A

1.01 (0.53-1.93)

Overdominant

G/G-A/A

1.00

0.68

G/G-A/A

1.00

0.78

G/G-A/A

1.00

0.66

A/G

0.88 (0.49-1.60)

A/G

1.06 (0.68-1.66)

A/G

1.12 (0.68-1.82)

Log-additive

---

1.18 (0.77-1.79)

0.44

---

1.23 (0.89-1.70)

0.2

---

1.07 (0.75-1.52)

0.72

Model

rs4818 genotypes

OR (95% CI)

P-value

rs4818 genotypes

OR (95% CI)

P-value

rs4818 genotypes

OR (95% CI)

P-value

Codominant

C/C

1.00

0.27

C/C

1.00

0.75

C/C

1.00

0.24

C/G

0.56 (0.28-1.14)

C/G

0.82 (0.48-1.41)

C/G

0.61 (0.34-1.09)

G/G

0.77 (0.33-1.81)

G/G

0.81 (0.41-1.59)

G/G

0.66 (0.32-1.38)

Dominant

C/C

1.00

0.15

C/C

1.00

0.45

C/C

1.00

0.095

C/G-G/G

0.62 (0.32-1.19)

C/G-G/G

0.82 (0.49-1.38)

C/G-G/G

0.63 (0.36-1.09)

Recessive

C/C-C/G

1.00

0.76

C/C-C/G

1.00

0.79

C/C-C/G

1.00

0.79

G/G

1.12 (0.54-2.32)

G/G

0.93 (0.53-1.63)

G/G

0.92 (0.49-1.71)

Overdominant

C/C-G/G

1.00

0.13

C/C-G/G

1.00

0.65

C/C-G/G

1.00

0.2

C/G

0.63 (0.35-1.15)

C/G

0.90 (0.58-1.41)

C/G

0.73 (0.44-1.19)

Log-additive

---

0.84 (0.54-1.31)

0.45

---

0.89 (0.64-1.25)

0.51

---

0.79 (0.55-1.14)

0.21