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Figure 3 | The Journal of Headache and Pain

Figure 3

From: Use of a fixed combination of acetylsalicylic acid, acetaminophen and caffeine compared with acetaminophen alone in episodic tension-type headache: meta-analysis of four randomized, double-blind, placebo-controlled, crossover studies

Figure 3

Proportion of all headache episodes and severe headache episodes at baseline that were pain-free at 2 h after treatment. AAC was significantly superior to APAP and placebo for all headache episodes (p < 0.0001 vs. both) and those that were severe at baseline (p < 0.0001 vs. APAP and p = 0.0003 vs. placebo). APAP was significantly superior to placebo for all headache episodes (p = 0.007) but not those that were severe at baseline (p = 0.71).

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The Journal of Headache and Pain

ISSN: 1129-2377

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