Skip to main content

Advertisement

Table 5 The genotype distribution of 5-HTTLPR and rs25531 gene polymorphism between TN patients stratified by treatment response

From: The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in Idiopathic Trigeminal Neuralgia patients

Genotype Treatment without improvement   Treatment with improvement   Adjusted OR 95% CI Adjusted P
5-HTTLPR Long-long 15 19.74% 46 32.62% 1.000    
  Long-short 39 51.32% 72 51.06% 1.661 0.824 3.349 0.154
  Short-short 22 28.95% 23 16.31% 2.933 1.285 6.696 0.009
  Long 69 45.39% 164 58.16% 1.000    
  short 83 54.61% 118 41.84% 1.672 1.124 2.488 0.011
rs25531 AA 13 17.11% 31 21.99% 1.000    
  AG 45 59.21% 76 53.90% 1.412 0.670 2.975 0.363
  GG 18 23.68% 34 24.11% 1.262 0.532 2.994 0.597
  A 71 46.71% 138 48.94% 1.000    
  G 81 53.29% 144 51.06% 1.093 0.737 1.623 0.851