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Table 5 The genotype distribution of 5-HTTLPR and rs25531 gene polymorphism between TN patients stratified by treatment response

From: The serotonin transporter gene polymorphism is associated with the susceptibility and the pain severity in Idiopathic Trigeminal Neuralgia patients

Genotype

Treatment without improvement

 

Treatment with improvement

 

Adjusted OR

95% CI

Adjusted P

5-HTTLPR

Long-long

15

19.74%

46

32.62%

1.000

   
 

Long-short

39

51.32%

72

51.06%

1.661

0.824

3.349

0.154

 

Short-short

22

28.95%

23

16.31%

2.933

1.285

6.696

0.009

 

Long

69

45.39%

164

58.16%

1.000

   
 

short

83

54.61%

118

41.84%

1.672

1.124

2.488

0.011

rs25531

AA

13

17.11%

31

21.99%

1.000

   
 

AG

45

59.21%

76

53.90%

1.412

0.670

2.975

0.363

 

GG

18

23.68%

34

24.11%

1.262

0.532

2.994

0.597

 

A

71

46.71%

138

48.94%

1.000

   
 

G

81

53.29%

144

51.06%

1.093

0.737

1.623

0.851