Skip to main content

Table 2 Rat MMA, 100 mmHg, pre-contracted with PGF 2α

From: Comparison of the vasodilator responses of isolated human and rat middle meningeal arteries to migraine related compounds

Compound

Emax(%)

pEC50(M)

p - value

ACh (n = 3)

33 ± 22

N.A.

0.68

SNP (n = 3)

70 ± 18

8.3 ± 0.7

0.066

Sildenafil (n = 3)

52 ± 20

~7

0.23

PGE2 (n = 3)

23 ± 12

N.A.

0.82

PACAP-38 (n = 4)

22 ± 14

N.A.

0.93

NaCl (n = 3)

23 ± 4

N.A.

 
  1. p-value for comparing agonist versus the NaCl effect. N.A. = Not Applicable. Values are ± SEM, n given in parenthesis.
Back to article page

The Journal of Headache and Pain

ISSN: 1129-2377

Contact us