Figure 2

Effect of telcagepant and sumatriptan on CGRP induced relaxation of the middle meningeal artery. Arteries were precontracted with 30 mM K⁺, dilated with 4 nM CGRP and sumatriptan or telcagepant was subsequently added (* = p < 0.05). Values are given as % of the CGRP relaxation (mean ± SEM, n = 5).