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Table 4 Studies on endothelial function by endothelial progenitor cells in migraineurs

From: Peripheral vascular dysfunction in migraine: a review

Study (First author, year)

Study design

Patients included (n)

% women

Exclusion criteria

Migraine diagnosis

Results

Lee, 2008 [36]

CC

Migraine: 92

70

CVD, diabetic retinopathy

ICHD-II

Decreased number and migratory capacity and higher senescence levels of endothelial progenitor cells in migraineurs versus controls

(MwoA: 67; MwA: 25)

Controls: 37

Oterino, 2013 [37]

CC

CM: 51

73

CVD, inflammatory disease, cancer or treatment with antimitogen agents, pregnancy in the last year

ICHD-I

Higher number of activated endothelial progenitor cells in migraineurs

EM: 48

Controls: 35

Rodriguez-Osorio, 2012 [23]

CC

Migraine : 47

98

CAD, inflammatory disease, obesity, HYP, DM, dyslipidemia, CS, infectious disease, severe systemic disease; ovarium pathology, pregnancy or lactation, use of vasoactive drugs

ICHD-II

Lower endothelial progenitor cell counts in migraineurs

(MwA:14; MwoA: 33)

  

Controls: 23

    
  1. CC case–control; CM chronic migraine; EM episodic migraine; MwA migraine with aura; MwoA migraine without aura; CVD cardiovascular disease; CAD coronary artery disease; HYP arterial hypertension; DM diabetes mellitus; CS cigarette smoking; ICHD International classification headache disorders.