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Table 2 Reported treatments for primary cough headache

From: Headache associated with cough: a review

Product [Reference] Recommended daily dose Most common side effects
Indomethacin [3] 50-150 mg peptic ulcers, dyspepsia, edema, hyperkalemia, hypernatremia, hypertension
Topiramate [33] 50-100 mg cognitive deficits, paresthesia, anorexia
Methysergide [9, 34, 35] 2 mg pleuritis, pericarditis, retroperitoneal fibrosis
Acetazolamide [25] 375-2200 mg paresthesia, parageusia, kidney stones, dehydration, headache, metabolic acidosis
Propranolol [35] 120 mg hypotension, bradycardia
Naproxen [37] 550-1100 mg gastrointestinal complaints
Metoclopramide [38] 10 mg intravenous bolus restlessness, drowsiness, dizziness, fatigue, and focal dystonia