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Table 3 Post-treatment outcomes

From: Nabilone for the treatment of medication overuse headache: results of a preliminary double-blind, active-controlled, randomized trial

 

Ibuprofen

Nabilone

 

Basal

Follow-up

Basal

Follow-up

HI

0.97 ± 0.1

0.86 ± 0.3

0.93 ± 0.1

0.65 ± 0.4*

DAI

2.02 ± 1.2

1.8 ± 1.3

2.34 ± 1.6

0.99 ± 0.8*

VAS

8 ± 1.6

6.75 ± 2.4

7.8 ± 1.7

5.55 ± 2.5**

HIT-6™

68.4 ± 5.7

63.1 ± 11.9

66.7 ± 4.8

64 ± 6.8*

  1. The post-treatment improvements occurred only in patients who received nabilone during the second period of treatment
  2. HI Headache Index, DAI daily analgesic intake, VAS Visual Analogue Scale; HIT-6™ Headache Impact Test
  3. Paired t test * p < 0.05 and ** p < 0.01 versus basal