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Table 3 Post-treatment outcomes

From: Nabilone for the treatment of medication overuse headache: results of a preliminary double-blind, active-controlled, randomized trial

  Ibuprofen Nabilone
  Basal Follow-up Basal Follow-up
HI 0.97 ± 0.1 0.86 ± 0.3 0.93 ± 0.1 0.65 ± 0.4*
DAI 2.02 ± 1.2 1.8 ± 1.3 2.34 ± 1.6 0.99 ± 0.8*
VAS 8 ± 1.6 6.75 ± 2.4 7.8 ± 1.7 5.55 ± 2.5**
HIT-6™ 68.4 ± 5.7 63.1 ± 11.9 66.7 ± 4.8 64 ± 6.8*
  1. The post-treatment improvements occurred only in patients who received nabilone during the second period of treatment
  2. HI Headache Index, DAI daily analgesic intake, VAS Visual Analogue Scale; HIT-6™ Headache Impact Test
  3. Paired t test * p < 0.05 and ** p < 0.01 versus basal