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Table 1 Epidemiological profiles and clinical features in NDPH (Kung et al.’s), NDPH (ICHD-II) and NDPH (mf)

From: Refining clinical features and therapeutic options of new daily persistent headache: a retrospective study of 63 patients in India

 

NDPH (Kung et al.’s), n (%)

NDPH (ICHD-II), n (%)

NDPH-mf, n (%)

p value

No. of patients

63

41 (65 %)

22 (35 %)

 

Age (years) (mean, range)

36.8 ± 12.8, 18–68

35.2 ± 11.5, 18–58

39.9 ± 14.1, 20–68

0.1585

Gender (female)

36 (57 %)

24 (59)

12 (55 %)

0.7946

Duration of illness

 Mean (SD)

27.5 ± 19.6 months

25.14 ± 19.4 months

29.7 ± 19.9 months

0.3774

 Range

3–72 months

4–60 months

3–60 months

 

Past history of TTH

18 (29)

13 (32)

5 (23)

0.5642

Past history of migraine

16 (25)

9 (22)

7 (32)

0.5446

Recalling onset day

21 (33)

14 (34)

7 (32)

1.000

Unilateral pain

11 (17)

4 (9)

7 (32)

0.0394*

Daily pain

63 (100)

41 (100)

22 (100)

1.000

Pain free period in a day

7 (11)

5 (12)

2 (9)

1.000

Type of pain

 Non-throbbing

63 (100)

41 (100)

22 (100)

1.000

 Throbbing

32 (51)

18 (54)

14 (64)

0.1877

Aggravation by physical activities

17 (27)

10 (24)

7 (32)

0.5619

Hampering routine activities/professional work

5 (8)

3 (7)

2 (9)

1.000

Associated features

 Nausea

31 (49)

12 (29)

19 (86)

0.0001*

 Vomiting

3 (5)

0 (0)

3 (14)

0.0388*

 Photophobia

21 (33)

7 (17)

14 (64)

0.0005*

 Phonophobia

12 (19)

3 (7)

9 (41)

0.0025*

Autonomic symptoms

 Conjunctival-injection/tearing

9 (14)

4 (9)

5 (23)

0.2564

Depression (self-reported)

12 (19)

8 (20)

4 (18)

1.000

Anxiety (self-reported)

10 (16)

7 (17)

3 (14)

1.000

Triggering factors

 None

29 (46)

19 (46)

10 (45)

1.000

 Infection

18 (29)

10 (24)

8 (36)

0.3850

 Injury

7 (11)

4 (9)

3 (14)

0.6871

 Stress

5 (8)

5 (12)

0.1530

 Surgery

3 (5)

2 (5)

1 (5)

1.000

 Post-partum

1 (2)

1 (2)

1.000

 Medication Overused

8 (13)

5 (12)

3 (14)

1.000

  1. NDPH (ICHD-II) new daily persistent headache according to second edition of the International Classification of Headache Disorders, NDPH-mf new daily persistent headache with prominent migrainous features, TTH tension-type headache