Table 15 Level of evidence, scientific strength of evidence, clinical effectiveness, adverse events of preventive drugs for SUNCT

Topiramate oral

75

C

0/+

++

Mild

2

[333]

Topiramate oral

50

C

0/+

+++

–

1

[334]

Carbamazepine oral

200

C

0/+

++

–

1

[335]

Carbamazepine oral

400

C

0/+

+++

–

1

[336]

Carbamazepine oral

600–1,000

C

0/+

?

–

5

[337–340]

Carbamazepine oral

2,000

C

0/+

?

–

1

[341]

Gabapentin oral

800–2,700

C

0/+

+++

–

3

[342–344]

Lamotrigine oral

100–200

C

0/+

++

–

12

[345–350]

Lamotrigine oral

300–400

C

0/+

+++

–

2

[351, 352]

Verapamil

480

C

0/+

?

–

1

[353]

Topiramate oral

200

C

0/+

+++

–

1

[354]

Methylprednisolone oral

≤1 /kg

C

0/+

+++

–

3

[355]

Oxcarbazepine and gabapentin oral

600/400

C

0/+

++

Mild

1

[356]

Lidocaine i.v.

1.3 /kg/h

C

0/+

+++

–

1

[357]