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Fig. 2 | The Journal of Headache and Pain

Fig. 2

From: Effect of CGRP and sumatriptan on the BOLD response in visual cortex

Fig. 2

a One-way voxel-wise ANOVA results from the measured time points at the CGRP day (left side) and placebo day (right side). ANOVA showed no statistical changes over time in activated voxels after CGRP and placebo infusion except some scattered activation after sumatriptan injection on CGRP day. The activated voxels were located primarily in the cerebellum and in the white matter of the corpus callosum (arrows). There were no activated voxels in the predefined visual region-of-interest. b Second level analysis revealed no statistical difference between two experimental days. The pictures show the mean subtracted values between placebo day and the CGRP day. c Baseline corrected contrast of parameter estimate (COPE1) results from the visual region-of-interest. ANOVA revealed no statistical changes after CGRP (P = 0.12) or placebo infusion (P = 0.41). We found no statistical difference between two experimental days (P = 0.357). ANOVA revealed no statistical changes after injection of sumatriptan either on the CGRP (P = 0.71) or on the placebo days (P = 0.98). We found no statistical after sumatriptan between two experimental days (P = 0.49)

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