Table 15 Diagnostic criteria for medication overuse headache [45]

A. Headache present on ≥15 days/month

B. Regular overuse for >3 months of one or more acute/symptomatic treatment drugs as defined under subforms of 8.2 medication overuse headache

 1. Ergotamine, triptans, opioids or combination analgesics ≥10 days/month on a regular basis for >3 months

 2. Simple analgesics or any combination of ergotamine, triptans or opioids for ≥15 days/month on a regular basis for >3 months without overuse of any single class alone

C. Headache has developed or markedly worsened during medication overuse