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Table 4 Reasons for non-adherence to pharmacological prophylaxis

From: Clinical outcome of a headache-specific multidisciplinary treatment program and adherence to treatment recommendations in a tertiary headache center: an observational study

Reason Number of patients (%a)
Ineffectiveness 19 (12.8)
Side effects 41 (27.6)
Fear of side effects 2 (1.4)
Pregnancy 4 (2.7)
Physician’s advice at MTP 13 (8.8)
Denial of daily medication intake 6 (4.1)
General non-compliance 14 (9.5)
Discontinuation 6 (9.5)
No further need because of improvement 9 (6.1)
Preference of non-pharmacological approaches 4 (2.7)
Contraindications 1 (0.7)
Advice of another person (change/termination of prophylaxis)b 47 (31.8) (40/7)
Not specified 8 (5.4)
  1. aPercentage of patients who did not ingest prescribed prophylaxis until follow-up; multiple answers were possible
  2. bAdvice of another person: after MTP, e.g., general practitioner, neurologist in private practice, physician in West German Headache Center; main reasons for change or termination were side effects (19%) and ineffectiveness (17%)