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Table 2 Result for the secondary study endpoints

From: A double-blind, randomized, multicenter, Italian study of frovatriptan versus rizatriptan for the acute treatment of migraine

 

ITT (n = 125)

p

PP (n = 96)

p

Frovatriptan

Rizatriptan

Frovatriptan

Rizatriptan

Pain-free episodes at 2 h

117 (33)

141 (39)

NS

107 (37)

116 (40)

NS

Recurrent episodes (IHS)

25 (21)

61 (43)

<0.001

21 (20)

40 (35)

<0.05

Recurrent episodes (protocol)

77 (22)

117 (32)

<0.001

61 (21)

91 (32)

<0.01

Sustained pain-free episodes

92 (26)

80 (22)

NS

86 (30)

76 (26)

NS

Pain relief episodes at 2 h

155 (55)

166 (62)

NS

129 (61)

134 (60)

NS

  1. Data are shown for the intention-to-treat and per-protocol population and reported as absolute (n) and relative (%) frequency. p refer to the statistical significance of the difference between the two treatment groups