Table 4 Distribution of allelic frequencies of CYP1A2 −163A > C SNP in the drug response classes assessed by Chi-test analysis
From: Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine
−163A > C (CYP1A2*1F) alleles | Therapy response grade | |||||||
|---|---|---|---|---|---|---|---|---|
0–25% (class 1) | 25–50% (class 2) | 50–75% (class 3) | 75–100% (class 4) | |||||
Obs. | Exp. | Obs. | Exp. | Obs. | Exp. | Obs. | Exp. | |
A | 29 | 27.4 | 25 | 20.2 | 15 | 18.7 | 39 | 41.8 |
C | 9 | 10.6 | 3 | 7.84 | 11 | 7.28 | 19 | 16.2 |