Table 5 Genotypic and allelic frequencies of 5-HT1A polymorphism in controls, migraine without aura and without drug overuse (MO) and medication overuse headache (MOH)
From: Lack of association between five serotonin metabolism-related genes and medication overuse headache
|  | Controls (n = 94) | MO (n = 96) | MOH (n = 99) |
|---|---|---|---|
5-HT1A (82) genotype | |||
 AA | 90 (0.96) | 88 (0.92) | 97 (0.98) |
 AG | 4 (0.04) | 8 (0.08) | 2 (0.002) |
MO versus controls | χ2 = 1.361 (P = 0.243) | ||
MOH versus controls | χ2 = 0.812 (P = 0.367) | ||
MOH versus MO | χ2 = 4.247 (P = 0.039)* | ||
5-HT1A alleles | |||
 A | 184 (0.98) | 184 (0.84) | 196 (0.99) |
 G | 4 (0.02) | 8 (0.04) | 2 (0.001) |
MO versus controls | χ2 = 1.29 (P = 0.256) | ||
MOH versus controls | χ2 = 0.79 (P = 0.376) | ||
MOH versus MO | χ2 = 3.88 (P = 0.049)* | ||