Table 3 Genotypic and allelic frequencies of 5-HT2A polymorphism in controls, migraine without aura and without drug overuse (MO) and medication overuse headache (MOH)
From: Lack of association between five serotonin metabolism-related genes and medication overuse headache
|  | Controls (n = 100) | MO (n = 98) | MOH (n = 101) |
|---|---|---|---|
n (%) | n (%) | n (%) | |
5-HT2A (102) genotype | |||
 CC | 25 (0.25) | 18 (0.18) | 23 (0.23) |
 CT | 50 (0.50) | 53 (0.54) | 58 (0.57) |
 TT | 25 (0.25) | 27 (0.28) | 20 (0.20) |
MO versus controls | χ2 = 1.289 (P = 0.525) | ||
MOH versus controls | χ2 = 1.228 (P = 0.541) | ||
MOH versus MO | χ2 = 1.838 (P = 0.399) | ||
5-HT2A alleles | |||
 C | 100 (0.50) | 89 (0.45) | 104 (0.52) |
 T | 100 (0.50) | 109 (0.55) | 98 (0.48) |
MO versus controls | χ2 = 0.83 (P = 0.361) | ||
MOH versus controls | χ2 = 0.09 (P = 0.766) | ||
MOH versus MO | χ2 = 1.47 (P = 0.226) | ||