Table 5 Preventive treatments in headache associated with panic disorder

Short-term treatment

BZDs: alprazolam, clonazepam

Long-term treatment

Migraine + panic disorder: VPA

Migraine + panic disorder + bipolar disorder: VPA

Migraine + panic disorder + secondary depression: antidepressants with sedative properties

 TCAs: amitriptyline

 SSRIs: paroxetine, fluvoxamine

 SNRIs: mirtazepine

Migraine + depression + secondary panic disorder

 Prevalence of anxiety symptoms: antidepressants with sedative properties

  TCAs: amitriptyline

  SSRIs: paroxetine, fluvoxamine

  SARI: trazodone

 Prevalence of psychomotor slowing: antidepressants without sedative properties

  SSRIs: fluoxetine