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Table 5 Preventive treatments in headache associated with panic disorder

From: Psychiatric comorbidity in patients with chronic daily headache and migraine: a selective overview including personality traits and suicide risk

Short-term treatment
BZDs: alprazolam, clonazepam
Long-term treatment
Migraine + panic disorder: VPA
Migraine + panic disorder + bipolar disorder: VPA
Migraine + panic disorder + secondary depression: antidepressants with sedative properties
 TCAs: amitriptyline
 SSRIs: paroxetine, fluvoxamine
 SNRIs: mirtazepine
Migraine + depression + secondary panic disorder
 Prevalence of anxiety symptoms: antidepressants with sedative properties
  TCAs: amitriptyline
  SSRIs: paroxetine, fluvoxamine
  SARI: trazodone
 Prevalence of psychomotor slowing: antidepressants without sedative properties
  SSRIs: fluoxetine
  1. VPA Valproate