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Table 1 Genotype distribution (GF) and allele frequencies (AF) of the AQP4 gene in migraine patients and controls

From: Investigating the genetic role of aquaporin4 gene in migraine

 

N

GF

AF

AQP4 SNP1 rs376043

 

A/A (%)

A/G (%)

G/G (%)

A (%)

G (%)

 Migraine patients

293

137 (46.7)

120 (41.0)

36 (12.3)

394 (67.2)

192 (32.8)

 Controls

249

122 (49.0)

100 (40.2)

27 (10.8)

344 (69.1)

154 (30.9)

AQP4 SNP3 rs35248760

 

C/C (%)

C/A (%)

A/A (%)

C

A

 Migraine patients

293

233 (79.5)

56 (19.1)

4 (1.4)

522 (89.1)

64 (10.9)

 Controls

249

198 (79.5)

48 (19.3)

3 (1.2)

444 (89.2)

54 (10.8)

AQP4 SNP4 rs162008

 

C/C (%)

C/T (%)

T/T (%)

C

T

 Migraine patients

293

193 (65.9)

90 (30.7)

10 (3.4)

476 (81.2)

110 (18.8)

 Controls

249

153 (61.4)

82 (32.9)

14 (5.6)

388 (77.9)

110 (22.1)

  1. P values were calculated by the χ2 test from 3 × 2 (genotype) or 2 × 2 (allele) contingency tables. No comparison showed significant difference