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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Anti-neuronal antibodies associated with headache with neurological deficits and cerebrospinal fluid lymphocytosis

Fig. 1

The binding pattern of HaNDL patients’ IgG with the rat cerebral and cerebellar nuclei is similar but somewhat distinctive from those of anti-Hu, anti-Ri and ANA positive serum samples (left two columns, original magnification ×100, counterstained with hematoxylin). ANA positive sera react with the nuclei of both the widespread intestinal and HEp-2 cells, anti-Hu positive sera only react with the nuclei of intestinal neuronal cells (arrow) and anti-Ri positive and HaNDL sera do not react with any of these tissues (right two columns, original magnification ×100, immunofluorescence, normal normal serum sample, G granular layer, P Purkinje cells, M molecular layer, ANA anti-nuclear antibody)

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