Skip to main content

Table 4 Selected studies reporting the risk of stroke in migraineurs

From: Comorbid neuropathologies in migraine: an update on cerebrovascular and cardiovascular aspects

Study

Age (years)

Sex

Total sample (n)

Any migraine (RR, 95%CI)

Migraine with aura (RR, 95%CI)

Migraine without aura (RR, 95%CI)

Buring [52]a, c

40–84

M

22,071

2.0, 1.1–3.6

NR

NR

Carolei [53]a, d

15–44

M, W

899

1.3, 0.7–2.4

8.6, 1.0–75

1.0, 0.5–2.0

Chang [54]a, c

20–44

W

1,027

3.5, 1.3–9.6

3.8, 1.3–11.5

3.0, 0.7–13.5

Henrich [59]a, d

15–65

M, W

267

1.8, 0.9–3.6

2.6, 1.1–6.6

1.3, 0.5–3.6

Kurth [60]a, c

≥45

W

39,754

1.4, 1.0–1.9

1.7, 1.1–2.7

1.1, 0.7–1.8

MacClellan [62]a, c

15–49

W

1,000

NR

1.5, 1.1–2.0

1.0, 0.6–1.5

Marini [63]a, d

15–44

M, W

616

NR

14.8, 1.8–124

1.6, 0.9–3.0

Merikangas [64]b, c

25–74

M, W

12,220

2.1, 1.5–2.9

NR

NR

Nightingale [67]a, c

15–49

W

1,319

2.3, 1.0–5.2

NR

NR

Schwaag [68]a, d

≤45

M, W

320

2.1, 1.2–3.8

NR

NR

Stang [70]a, c

45–64

M, W

12,750

NR

2.7, 1.6–4.6

0.8, 0.4–1.5

Tzourio [71]a, d

18–80

M, W

424

1.3, 0.8–2.3

1.3, 0.5–3.8

0.8, 0.4–1.5

Tzourio [72]a, c

<45

W

245

3.5, 1.8–6.4

6.2, 2.1–18.0

3.0, 1.5–5.8

  1. NR not reported; M men; W women
  2. aStudies including only ischemic strokes
  3. bStudies including ischemic and hemorrhagic strokes
  4. cAdjusted risk
  5. dUnadjusted risk