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Table 1 Effect of patent foramen ovale closure on migraine in non-randomized studies in which the closure was performed for other reasons than migraine

From: Comorbid neuropathologies in migraine: an update on cerebrovascular and cardiovascular aspects

Study

 

Patients reporting cessation (%)

Patients reporting improvement (%)

Patients reporting no effect (%)

 

Time to assessment

Migraine with aura

Migraine without aura

Migraine with aura

Migraine without aura

Migraine with aura

Migraine without aura

Anzola [17]

1 year

34

41

53

47

13

12

Azarbal [19]

3 months

75

40

5

40

20

20

Giardini [20]

1.7 years

83

–

9

–

8

–

Post [23]

6 months

75

57

NR

NR

NR

NR

Reisman [24]

37 weeks

54

62

14

15

32

23

Rigatelli [25]

11 months

100

–

0

–

0

–

Schwerzmann [27]

1 year

NR

NR

79

90

21

10

Wilmshurst [28]

17 months

44

60

50

0

6

40

  1. NR not reported