The Journal of Headache and Pain

Featured Articles: September, 2024

Targeting IGF1/IGF1r signaling relieve pain and autophagic dysfunction in NTG-induced chronic migraine model of mice

Influence of next-generation artificial intelligence on headache research, diagnosis and treatment: the junior editorial board members’ vision – part 1

Celebrating 25 years of The Journal of Headache and Pain

This year marks the 25th anniversary of The Journal of Headache and Pain! We are celebrating the journal's success over the past 25 years and recognising the contributions of scientists from around the world who have made the journal into what it is today.

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Call for papers

AI Advancements in Headache Research: Navigating the Digital Frontier

Edited by: Gianluca Coppola and Igor Petrušić

This collection explores the use of machine learning in migraine research, focusing on advanced algorithms and computational techniques to analyze clinical and neuroimaging data, aiming to uncover patterns and relationships with digital twin solutions.

Endogenous Treatments for Migraine Pain

Edited by: Adriana Della Pietra and Andrew Russo

This collection aims to provide a better understanding of the basic molecular mechanisms of endogenous pain management. This may lead to better and/or alternative migraine pain treatments based on an enhancement of endogenous analgesic systems.

Headache Burden in Children and Adolescents

Edited by: Marco Antônio Arruda and Timothy J. Steiner

This series will embrace estimates from worldwide of headache-attributed burden, studies characterising the headache disorders of childhood and their evolution throughout adolescence (especially longitudinal cohort studies), those providing insights into the diagnostic uncertainties of child and adolescent headache, and those proposing or evaluating systems of care for child and adolescent headache.

Spreading Depolarization in Headache Disorders

Edited by: Shih Pin Chen and Cenk Ayata

This new collection in The Journal of Headache and Pain invites researchers, clinicians, and academicians to discuss spreading depolarization, exploring its mechanisms, relevance, and implications in both primary and secondary neurological disorders.

Vascular Triggers of Headache Disorders

Edited by: Shih Pin Chen and Cenk Ayata

The Journal of Headache and Pain invites submissions on the interplay between vascular mechanisms and headache, particularly migraine, to our new Collection: Vascular Triggers of Headache.

Gender-Specific Aspects of Headache

Edited by: Antoinette Maassen van den Brink and Bianca Raffaelli

The Journal of Headache and Pain is calling for submissions to our Collection on Gender-Specific Aspects of Headache. This collection aims to explore the multifaceted relationship between gender (as well as biological sex) and headache, encompassing both biological and socio-cultural dimensions.

Article collections

Click here to see the article collections and thematic series that the journal has published in recent years.

Exploring SDG3: Good Health and Wellbeing

Collaborative evidence-based approaches to public policy and healthcare policy and practice are essential, not only in addressing inequalities but also in building trusted sustainable ways forward in which to ensure good health and wellbeing for all. The Journal of Headache and Pain supports submissions that address the SDG3 targets and indicators.

The Journal of Headache and Pain encourages authors to submit a visual abstract as a supplementary file along with their manuscripts.

As an author submitting at The Journal of Headache and Pain you are entitled to a 20% discount on professionally produced visual abstracts. Click here to find out more about the service, and your discount will be automatically applied when using this link.

Aims and scope

The Journal of Headache and Pain is a peer-reviewed open access journal specifically dedicated to researchers involved in all aspects of headache and related pain syndromes, including epidemiology, public health, basic science, translational medicine, clinical trials and real-world data. With a multidisciplinary perspective, The Journal of Headache and Pain covers headache medicine and related pain syndromes in all medical disciplines and particularly encourages clinical, translational and basic science submissions in the areas of pain management, genetics, neurology and internal medicine. Read more.

Partnering with the Asian Regional Consortium for Headache (ARCH)

We are delighted to welcome the Asian Regional Consortium for Headache (ARCH) as a partner of The Journal of Headache and Pain. ARCH joins the European Headache Federation and Lifting The Burden in affiliating with the journal. Read more about this partnership here.

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Articles

Disrupted gray matter connectome in vestibular migraine: a combined machine learning and individual-level morphological brain network analysis

Authors: Wen Chen, Hongru Zhao, Qifang Feng, Xing Xiong, Jun Ke, Lingling Dai and Chunhong Hu

Content type: Research 11 October 2024
Gender-different effect of Src family kinases antagonism on photophobia and trigeminal ganglion activity

Authors: Zhuoan Huang, Junyu Yao, Lingdi Nie, Xinchen Nie, Xuechunhui Xiong, Sulev Kõks, John P. Quinn, Aditi Kanhere and Minyan Wang

Content type: Research 11 October 2024
Differential expression of components of the CGRP-receptor family in human coronary and human middle meningeal arteries: functional implications

Authors: Tessa de Vries, Dennis Schutter, Antoon van den Bogaerdt, Arnaud Vincent, Ruben Dammers, A. H. Jan Danser and Antoinette MaassenVanDenBrink

Content type: Research 10 October 2024
Pediatric migraine is characterized by traits of ecological and metabolic dysbiosis and inflammation

Authors: Laura Papetti, Federica Del Chierico, Ilaria Frattale, Francesca Toto, Matteo Scanu, Stefano Levi Mortera, Federica Rapisarda, Marta Di Michele, Gabriele Monte, Fabiana Ursitti, Giorgia Sforza, Lorenza Putignani and Massimiliano Valeriani

Content type: Research 9 October 2024
Health-related quality of life among women and men living with migraine: a Canada-wide cross-sectional study

Authors: Alexander C.T. Tam, Hiten Naik, Logan Trenaman, Larry Lynd and Wei Zhang

Content type: Research 9 October 2024

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Headache in transient ischemic attacks

Authors: Elena R. Lebedeva, Natalia M. Gurary and Jes Olesen

Content type: Research article 27 July 2018
Delayed headache after COVID-19 vaccination: a red flag for vaccine induced cerebral venous thrombosis

Authors: David García-Azorín, Thien Phu Do, Andreas R. Gantenbein, Jakob Møller Hansen, Marcio Nattan P. Souza, Mark Obermann, Heiko Pohl, Christoph J. Schankin, Henrik Winther Schytz, Alexandra Sinclair, Guus G. Schoonman and Espen Saxhaug Kristoffersen

Content type: Short report 17 September 2021
Long COVID headache

Authors: Claudio Tana, Enrico Bentivegna, Soo-Jin Cho, Andrea M. Harriott, David García-Azorín, Alejandro Labastida-Ramirez, Raffaele Ornello, Bianca Raffaelli, Eloísa Rubio Beltrán, Ruth Ruscheweyh and Paolo Martelletti

Content type: Review 1 August 2022
Headache characteristics in COVID-19 pandemic-a survey study

Authors: Özge Uygun, Mustafa Ertaş, Esme Ekizoğlu, Hayrunnisa Bolay, Aynur Özge, Elif Kocasoy Orhan, Arif Atahan Çağatay and Betül Baykan

Content type: Research article 13 October 2020
Headache medication and the COVID-19 pandemic

Authors: Antoinette MaassenVanDenBrink, Tessa de Vries and A. H. Jan Danser

Content type: Commentary 25 April 2020

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Top cited articles 2021-2022

Review article | 12 April 2022
The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates December 2020
Lars Jacob Stovner, Knut Hagen, Mattias Linde & Timothy J. Steiner

Consensus article | 11 June 2022
European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention-2022 update
Simona Sacco, Faisal Mohammad Amin, Messoud Ashina, Lars Bendtsen, Christina I. Deligianni, Raquel Gil-Gouveia, Zaza Katsarava, Antoinette MaassenVanDenBrink, Paolo Martelletti, Dimos-Dimitrios Mitsikostas, Raffaele Ornello, Uwe Reuter, Margarita Sanchez-del-Rio, Alexandra J. Sinclair, Gisela Terwindt, Derya Uluduz, Jan Versijpt & Christian Lampl

Review article | 10 June 2021
Migraine and neuroinflammation: the inflammasome perspective
Oguzhan Kursun, Muge Yemisci, Arn M. J. M. van den Maagdenberg & Hulya Karatas

Research article | 3 May 2021
Galcanezumab for the prevention of high frequency episodic and chronic migraine in real life in Italy: a multicenter prospective cohort study (the GARLIT study)
Fabrizio Vernieri, Claudia Altamura, Nicoletta Brunelli, Carmelina Maria Costa, Cinzia Aurilia, Gabriella Egeo, Luisa Fofi, Valentina Favoni, Giulia Pierangeli, Carlo Lovati, Marco Aguggia, Florindo d’Onofrio, Alberto Doretti, Paola Di Fiore, Cinzia Finocchi, Renata Rao, Francesco Bono, Angelo Ranieri, Maria Albanese, Sabina Cevoli & Piero Barbanti for the GARLIT Study Group

Review article | 14 July 2021
Comorbidities of primary headache disorders: a literature review with meta-analysis
Valeria Caponnetto, Manuela Deodato, Micaela Robotti, Maria Koutsokera, Valeria Pozzilli, Cristina Galati, Giovanna Nocera, Eleonora De Matteis, Gioacchino De Vanna, Emanuela Fellini, Gleni Halili, Daniele Martinelli, Gabriele Nalli, Serena Serratore, Irene Tramacere, Paolo Martelletti & Alberto Raggi On behalf of the European Headache Federation School of Advanced Studies (EHF-SAS)

Research article | 25 October 2021
CGRP monoclonal antibodies in migraine: an efficacy and tolerability comparison with standard prophylactic drugs
Fenne Vandervorst, Laura Van Deun, Annelies Van Dycke, Koen Paemeleire, Uwe Reuter, Jean Schoenen & Jan Versijpt

Review article | 1 August 2022
Long COVID headache
Claudio Tana, Enrico Bentivegna, Soo-Jin Cho, Andrea M. Harriott, David García-Azorín, Alejandro Labastida-Ramirez, Raffaele Ornello, Bianca Raffaelli, Eloísa Rubio Beltrán, Ruth Ruscheweyh & Paolo Martelletti

Research article | 21 April 2021
Disability, quality of life, productivity impairment and employer costs of migraine in the workplace
Toshihiko Shimizu, Fumihiko Sakai, Hitoshi Miyake, Tomofumi Sone, Mitsuhiro Sato, Satoshi Tanabe, Yasuhiro Azuma & David W. Dodick

Short Report | 7 October 2021
Anti-CGRP monoclonal antibodies in chronic migraine with medication overuse: real-life effectiveness and predictors of response at 6 months
Edoardo Caronna, Victor José Gallardo, Alicia Alpuente, Marta Torres-Ferrus & Patricia Pozo-Rosich

Research article | 3 January 2022
IL-17 crosses the blood-brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine
Hao Chen, Xueqian Tang, Jin Li, Bangyan Hu, Wenqin Yang, Meng Zhan, Tengyun Ma & Shijun Xu

_{Publication years: 2021-2022
Source: Web of Science, data collected: January 2024}

European Headache Federation School of Advanced Studies

The European HeadacheFederation School of Advanced Studies (EHF-SAS) aims to support headache science and offers young EU scientists high quality educational activities to enhance their critical spirit and skills to face headache medicine from a multidisciplinary perspective.

The EHF-SAS covers the richness and diversity of headache medicine fields, including basic science, clinical science, and diagnostic science, and places an emphasis on collaborative projects. The European Headache Federation will support its fellows’ activities allowing them to independently build their own plan sided by the EHF-SAS Scientific Committee.