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A patient with trigeminal neuralgia may need different forms of treatment during his or her lifetime. Physicians should be aware of the different available surgical treatments, and know their effectiveness, s...
The localization of dopamine D1-D5 receptor protein was investigated in different sized dog pial arteries. This was done to further understand the pathophysiology of cerebrovascular dopaminergic system in mig...
Pain is a common situation and it is one of the most frequent presenting symptoms of different pathologies. Treating pain could be a precise request to the doctor, from the patient and his caregiver. Manageme...
Nitric oxide (NO) has been proposed to be a key molecule in migraine. Experimental evidence suggests its intervention in vasodilatation and activation of the trigeminovascular system as well as its involvemen...
Migraine and epilepsy are common neurological conditions that often co-exist. There are some common symptoms and in some patients there may be a diagnostic problem. The purpose of this study was to review the...
Although chronic daily headache (CDH) represents one of the most relevant complaints of patients in headache centers, the mechanisms underlying the chronicization of head pain are poorly understood. Experimen...
This article is part of a Supplement: Volume 1 Supplement 1
Pathophysiological studies have dominated migraine research for several years. However, these studies are difficult to interpret because it is difficult to decide whether the observed phenomena are primary or...
This article is part of a Supplement: Volume 1 Supplement 2
Migraine carries a significant hereditary determination. Familial hemiplegic migraine (FHM) has been recently linked to mutations in the CACNA1A gene on chromosome 19. CACNA1A codes for a subunit of a neural ...
This article is part of a Supplement: Volume 1 Supplement 2
Familial hemiplegic migraine (FHM) is an autosomal dominant subtpye of migraine with aura. A few years ago, the gene linked to FHM was identified. CACNA1A encodes a voltage-activated, pore-forming α1A subunit...
This article is part of a Supplement: Volume 1 Supplement 2
The major histocompatibility complex (MHC) is a genetic system of over 70 known genes on the short arm of chromosome 6 and spans about 4 million base pairs of DNA. The high resolution typing of class I and cl...
This article is part of a Supplement: Volume 1 Supplement 2
We describe a case of transient global amnesia (TGA) occurring as migraine aura. TGA prevalence is higher among migraineurs and has been ascribed to spreading depression in the hippocampus. Our patient, a 38-...
Abnormal pain reactivity is often reported by the parents of children with autistic disorder (AD). This is an interesting feature because it could be related to some neurochemical findings frequently reported...
The migraine disability assessment questionnaire (MIDAS) is a recently developed, validated questionnaire for assessing the impact of migraine on individual patients. We carried out a pilot study to assess th...
We sought out alterations of early trigeminal evoked potenials (TEPs) in patients suffering from episodic cluster headache, in order to evaluate a possible direct involvement of the trigeminal nerve. The stud...
Recurrent vertigo is a special form of migraine in childhood. It is a periodic syndrome of childhood which was previously called migraine equivalent. Thirty young patients (less than 18 years of age) with mig...
Oral sumatriptan in 100-mg tablets is an effective and well tolerated treatment for the acute migraine attack. Since the launch of that dose, further studies have suggested good efficacy also for lower doses....
The purpose of this observational-retrospective study was to assess which type of conjunctival injection and related phenomena are present during SUNCT attacks. We studied the videorecords of 23 SUNCT attacks...
A multicenter study was carried out to investigate the prevalence of psychosocial stressors and psychiatric comorbidity in patients suffering from migraine without aura (MWO) according to the International He...
To study changes in headache prevalence during childhood, adolescence and early adulthood, we performed a prospective long-term follow-up study on an unselected child population. Seven-year-old children, resi...
Recent years have seen exciting advances in the understanding of the mechanisms that underlie circadian rhythms in a variety of organisms, including mammals. Several key genes have been identified, whose prod...
The Journal of Headache and Pain is the official journal of the European Headache Federation and Lifting The Burden.
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