| CM + MO n = 71 mean ± SD | EM n = 61 mean ± SD | HC n = 80 mean ± SD |
---|---|---|---|
Inclusion criteria | a) age > 18, < 65 years b) ICHD-III criteria for CM + MO2 | a) age > 18, < 65 years b) ICHD-III criteria for EM2 c) migraine duration ≥ 10 years d) no history of CM | age > 18, < 65 years |
Exclusion criteria | a) dementia b) psychosis c) mental retardation | a) dementia b) psychosis c) mental retardation | a) personal or family history of migraine b) dementia c) psychosis d) mental retardation |
Age | 43.89 ± 8.94* | 41.54 ± 10.43 | 38.00 ± 11.88* |
Gender (female %) | 83% | 84% | 66% |
Years of education | 13.29 ± 3.48 | 14.39 ± 2.76 | 14.00 ± 3.13 |
Vocabulary | 46.18 ± 2.44 | 45.95 ± 2.79 | 45.76 ± 2.48 |
Age at onset (years) | 14.35 ± 8.04 | 16.44 ± 8.29 | - |
Duration of chronic headache (months) | 68.29 ± 67.32 | - | - |
Days with headache per month | 26.22 ± 4.76 | 6.48 ± 2.85 | - |
Days with intake per month | 24.20 ± 5.71 | - | - |
Drug doses per month | 41.01 ± 28.62 | - | - |
Class of overused acute drug | Â | - | - |
 NSAIDs | 18% | - | - |
 Triptans | 24% | - | - |
 Combination | 50% | - | - |
 Multiple drug classes | 8% | - | - |
Patients on prophylaxis treatment | 38% | - | - |
 Amitriptyline | 22% | - | - |
 Propranolol | 10% |  |  |
 Venlafaxine | 3% | - | - |
 Topiramate | 6% | - | - |